BDBM50192378 9-hydroxy-4-[4-(trifluoromethyl)phenyl]pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL215706

SMILES Oc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=RQZGMIPFEAGGAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192378   

TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50192378(9-hydroxy-4-[4-(trifluoromethyl)phenyl]pyrrolo[3,4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition at human Chk1 in presence of 4 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50192378(9-hydroxy-4-[4-(trifluoromethyl)phenyl]pyrrolo[3,4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Wee1 in presence of 9.5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed