BDBM50192490 (7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-(4-fluoro-phenyl)-amine::CHEMBL386998
SMILES COc1cc2CNc3c(Nc4ccc(F)cc4)ncnc3Oc2cc1OC
InChI Key InChIKey=VXNUNRFSHHUSIE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50192490
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of EGFR autophosphorylation in DiFi cells by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Imclone Systems
Curated by ChEMBL
Imclone Systems
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assayMore data for this Ligand-Target Pair