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BDBM50192856 CHEMBL3358989

SMILES: COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccnc1

InChI Key: InChIKey=QBPRTPTUVRCMLX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192856   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50192856
PNG
(CHEMBL3358989)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1cccnc1
Show InChI InChI=1S/C18H17N3O4/c1-23-14-7-12(8-15(24-2)17(14)25-3)16-18(22)20-10-13(21-16)11-5-4-6-19-9-11/h4-10H,1-3H3,(H,20,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Christian-Albrechts-University of Kiel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate


J Med Chem 58: 170-82 (2015)


Article DOI: 10.1021/jm500373x
BindingDB Entry DOI: 10.7270/Q2ZG6V0R
More data for this
Ligand-Target Pair