BDBM50193145 2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)acetic acid::CHEMBL426560::Isoquinoline 3::N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE

SMILES: c1ccc2c(c1)c(c(nc2Cl)C(=O)NCC(=O)O)O

InChI Key: InChIKey=OUQVKRKGTAUJQA-UHFFFAOYSA-N

Data: 1 KI  25 IC50  3 Kd  1 EC50

PDB links: 19 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50193145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	424	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-butyrobetaine dioxygenase (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A [1-973] (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase (PBCV-1)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+5	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2A (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 3A (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4E (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C [1-973] (Human)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase (PBCV-1)	BDBM50193145 (Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...) Show SMILES Show InChI	GoogleScholar	UniChem		710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair