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BDBM50193625 2-propyl-N6-(3-(4-(trifluoromethyl)phenyl)propyl)quinoline-4,6-diamine::CHEMBL216372

SMILES: CCCc1cc(N)c2cc(NCCCc3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=WJIUPZOJOQMODR-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193625   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (human))
BDBM50193625
PNG
(2-propyl-N6-(3-(4-(trifluoromethyl)phenyl)propyl)q...)
Show SMILES CCCc1cc(N)c2cc(NCCCc3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1S/C22H24F3N3/c1-2-4-18-14-20(26)19-13-17(10-11-21(19)28-18)27-12-3-5-15-6-8-16(9-7-15)22(23,24)25/h6-11,13-14,27H,2-5,12H2,1H3,(H2,26,28)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Similars

Article
PubMed
n/an/a 180n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1


Bioorg Med Chem Lett 16: 5275-9 (2006)

More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor


(Homo sapiens (human))
BDBM50193625
PNG
(2-propyl-N6-(3-(4-(trifluoromethyl)phenyl)propyl)q...)
Show SMILES CCCc1cc(N)c2cc(NCCCc3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1S/C22H24F3N3/c1-2-4-18-14-20(26)19-13-17(10-11-21(19)28-18)27-12-3-5-15-6-8-16(9-7-15)22(23,24)25/h6-11,13-14,27H,2-5,12H2,1H3,(H2,26,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 1.00E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing MCH-R1


Bioorg Med Chem Lett 16: 5275-9 (2006)

More data for this
Ligand-Target Pair