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BDBM50193692 1-(6-(3-(4-(trifluoromethyl)phenyl)propanamido)quinolin-2-yl)pyrrolidin-3-ylsulfamic acid::CHEMBL386211

SMILES: OS(=O)(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=VGOMLVGCPHXARJ-UHFFFAOYNA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193692   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GPR24


(RAT)
BDBM50193692
PNG
(1-(6-(3-(4-(trifluoromethyl)phenyl)propanamido)qui...)
Show SMILES OS(=O)(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1/C23H23F3N4O4S/c24-23(25,26)17-5-1-15(2-6-17)3-10-22(31)27-18-7-8-20-16(13-18)4-9-21(28-20)30-12-11-19(14-30)29-35(32,33)34/h1-2,4-9,13,19,29H,3,10-12,14H2,(H,27,31)(H,32,33,34)
Reactome pathway
KEGG

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 50n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1


Bioorg Med Chem Lett 16: 5270-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.006
BindingDB Entry DOI: 10.7270/Q2ZC82HP
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50193692
PNG
(1-(6-(3-(4-(trifluoromethyl)phenyl)propanamido)qui...)
Show SMILES OS(=O)(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1/C23H23F3N4O4S/c24-23(25,26)17-5-1-15(2-6-17)3-10-22(31)27-18-7-8-20-16(13-18)4-9-21(28-20)30-12-11-19(14-30)29-35(32,33)34/h1-2,4-9,13,19,29H,3,10-12,14H2,(H,27,31)(H,32,33,34)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1


Bioorg Med Chem Lett 16: 5270-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.006
BindingDB Entry DOI: 10.7270/Q2ZC82HP
More data for this
Ligand-Target Pair