BDBM50193772 1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-amino-2-oxoethyl)piperidin-2-yl)propyl)-3-(3,5-diacetylphenyl)urea::CHEMBL385607

SMILES CC(=O)c1cc(NC(=O)NCCC[C@H]2C[C@H](Cc3ccc(F)cc3)CCN2CC(N)=O)cc(c1)C(C)=O

InChI Key InChIKey=BRTWZDQCGNRNRK-LVXARBLLSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50193772   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193772(1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-amino-2-oxoe...)
Affinity DataKi:  710nMAssay Description:Inhibition of 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193772(1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-amino-2-oxoe...)
Affinity DataKi:  2.66E+3nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193772(1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-amino-2-oxoe...)
Affinity DataKi:  5.01E+3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193772(1-(3-((2S,4R)-4-(4-fluorobenzyl)-1-(2-amino-2-oxoe...)
Affinity DataIC50:  3.60nMAssay Description:Binding affinity to CCR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed