BDBM50193830 1-((3S,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-3-(1H-indol-3-yl)propan-1-one::CHEMBL387169
SMILES O=C(CCc1c[nH]c2ccccc12)N1C[C@@H]2CCCN2C[C@@H]1Cc1ccccc1
InChI Key InChIKey=KPKOJXZVOJTTBP-VXKWHMMOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50193830
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC3R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC5R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC1R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC4R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair