BDBM50194018 3-hydroxy-N-1-hydroxypropan-2-yl)-5-4-2-phenylpropan-2-yl)phenylamino)isothiazole-4-carboximidamide::CHEMBL385703

SMILES CC(CO)N=C(N)c1c(Nc2ccc(cc2)C(C)(C)c2ccccc2)s[nH]c1=O

InChI Key InChIKey=CNFOJUNYPYUQSD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194018   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194018(3-hydroxy-N-1-hydroxypropan-2-yl)-5-4-2-phenylprop...)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194018(3-hydroxy-N-1-hydroxypropan-2-yl)-5-4-2-phenylprop...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed