BDBM50194027 5-3-chloro-4-2-chloro-4-fluorophenoxy)phenylamino)-3-hydroxy-N-1-hydroxypropan-2-yl)isothiazole-4-carboximidamide::CHEMBL384784

SMILES CC(CO)N=C(N)c1c(Nc2ccc(Oc3ccc(F)cc3Cl)c(Cl)c2)s[nH]c1=O

InChI Key InChIKey=OCHNDLRNKXIWHR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194027   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194027(5-3-chloro-4-2-chloro-4-fluorophenoxy)phenylamino)...)
Affinity DataEC50:  37nMAssay Description:Inhibitory activity against MEK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194027(5-3-chloro-4-2-chloro-4-fluorophenoxy)phenylamino)...)
Affinity DataIC50:  107nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed