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BDBM50194226 (+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]non-7-yl]-1-(1-naphthyl)cyclopentanecarboxamide::CHEMBL215799

SMILES: C[C@H]1CN(CCCc2ccccc2)[C@@H]2C[C@H](C[C@]1(C2)c1cccc(O)c1)NC(=O)C1(CCCC1)c1cccc2ccccc12

InChI Key: InChIKey=UIEAIJWWPQRFLC-YSKMISTLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194226   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid receptors; mu/kappa/delta


(Homo sapiens (Human))
BDBM50194226
PNG
((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Show SMILES C[C@H]1CN(CCCc2ccccc2)[C@@H]2C[C@H](C[C@]1(C2)c1cccc(O)c1)NC(=O)C1(CCCC1)c1cccc2ccccc12
Show InChI InChI=1S/C40H46N2O2/c1-29-28-42(23-11-14-30-12-3-2-4-13-30)34-25-33(26-40(29,27-34)32-17-10-18-35(43)24-32)41-38(44)39(21-7-8-22-39)37-20-9-16-31-15-5-6-19-36(31)37/h2-6,9-10,12-13,15-20,24,29,33-34,43H,7-8,11,14,21-23,25-28H2,1H3,(H,41,44)/t29-,33+,34+,40+/m0/s1
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Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...


J Med Chem 49: 5597-609 (2006)


Article DOI: 10.1021/jm060459p
BindingDB Entry DOI: 10.7270/Q2H41R21
More data for this
Ligand-Target Pair