BDBM50194556 CHEMBL221445::N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro-2-phenyl-quinoline-4-carbonyl]-N-phenyl-hydrazinecarboxylic acid methyl ester

SMILES: COC(=O)N(NC(=O)c1c(CN2CCN(CC2)C(C)(C)C)c(nc2c(F)cccc12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=KQNYTTDHCMFOME-UHFFFAOYSA-N

Data: 1 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50194556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Substance-K receptor (Human)	BDBM50194556 (N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Substance-P receptor (Human)	BDBM50194556 (N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50194556 (N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neuromedin-K receptor (Human)	BDBM50194556 (N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50194556 (N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neuromedin-K receptor (Human)	BDBM50194556 (N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50194556 (N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50194556 (N'-[3-(4-tert-butyl-piperazin-1-ylmethyl)-8-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		>9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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