BDBM50194559 CHEMBL218321::N-phenyl-N'-{2-phenyl-3-[1-(tetrahydro-pyran-4-yl)-piperidin-4-yloxy]-quinoline-4-carbonyl}-hydrazinecarboxylic acid methyl ester

SMILES COC(=O)N(NC(=O)c1c(OC2CCN(CC2)C2CCOCC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=SUZFCPKCWBVLKR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194559   

TargetNeuromedin-K receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194559(N-phenyl-N'-{2-phenyl-3-[1-(tetrahydro-pyran-4-yl)...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]neurokinin B from human cloned NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194559(N-phenyl-N'-{2-phenyl-3-[1-(tetrahydro-pyran-4-yl)...)
Affinity DataKi:  8.90E+3nMAssay Description:Displacement of labeled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed