BDBM50194568 CHEMBL221299::N-phenyl-N'-(2-phenyl-3-piperazin-1-ylmethyl-quinoline-4-carbonyl)-hydrazinecarboxylic acid methyl ester

SMILES COC(=O)N(NC(=O)c1c(CN2CCNCC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=LXVHCKLEUVVBBN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194568   

TargetNeuromedin-K receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194568(N-phenyl-N'-(2-phenyl-3-piperazin-1-ylmethyl-quino...)
Affinity DataIC50: 34nMAssay Description:Displacement of [125I]neurokinin B from human cloned NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194568(N-phenyl-N'-(2-phenyl-3-piperazin-1-ylmethyl-quino...)
Affinity DataKi:  840nMAssay Description:Displacement of labeled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed