BDBM50194643 (2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-((3R)-3-piperidinylmethyl)-pyrrolidine-2-carboxamide::CHEMBL215894
SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)N1CCC[C@@H]1C(=O)NC[C@@H]1CCCNC1
InChI Key InChIKey=AFAZXESEAHMGAC-BMSWWXRLSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50194643
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of [3H]NMS binding to human cloned M2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Inhibition of [3H]NMS binding to human cloned M4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Inhibition of [3H]NMS binding to human cloned M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of [3H]NMS binding to human cloned M5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair