BDBM50194668 4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide::CHEMBL215943

SMILES: Cc1ccc(cc1-c1ccc2nc(NCCN3CCOCC3)ncc2c1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=DVRSTRMZTAPMKO-UHFFFAOYSA-N

Data: 20 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50194668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	292	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-5 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 2 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	545	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit beta (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50194668 (4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
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