BDBM50194693 6-o-tolylquinazolin-2-amine::CHEMBL215952

SMILES Cc1ccccc1-c1ccc2nc(N)ncc2c1

InChI Key InChIKey=RAWAQXBVMDKSIO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194693   

TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50194693(6-o-tolylquinazolin-2-amine | CHEMBL215952)
Affinity DataIC50: 94nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50194693(6-o-tolylquinazolin-2-amine | CHEMBL215952)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50194693(6-o-tolylquinazolin-2-amine | CHEMBL215952)
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50194693(6-o-tolylquinazolin-2-amine | CHEMBL215952)
Affinity DataIC50: 9.82E+3nMAssay Description:Inhibition of Jak3 by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed