BDBM50194950 2-((6-(2-(2-(4-methoxyphenyl)-5-methyloxazol-4-yl)ethoxy)pyridin-3-yl)methyl)-tetrahydrofuran-2-carboxylic acid::CHEMBL221649

SMILES COc1ccc(cc1)-c1nc(CCOc2ccc(CC3(CCCO3)C(O)=O)cn2)c(C)o1

InChI Key InChIKey=HEIQVRRGXSCNIH-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194950   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50194950(2-((6-(2-(2-(4-methoxyphenyl)-5-methyloxazol-4-yl)...)
Affinity DataKi:  17nMAssay Description:Displacement of radiolabeled darglitazone from human PPAR gamma by SPA binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50194950(2-((6-(2-(2-(4-methoxyphenyl)-5-methyloxazol-4-yl)...)
Affinity DataEC50:  65nMAssay Description:Displacement of radiolabeled GW2331 from human PPAR alpha by SPA binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50194950(2-((6-(2-(2-(4-methoxyphenyl)-5-methyloxazol-4-yl)...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human PPAR gamma in a HepG2 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50194950(2-((6-(2-(2-(4-methoxyphenyl)-5-methyloxazol-4-yl)...)
Affinity DataEC50:  486nMAssay Description:Agonist activity at human PPAR alpha in a HepG2 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed