BDBM50195 4,4,6-Trimethyl-1-[4-oxo-2-thioxo-thiazolidin-(5Z)-ylidene]-6-phenyl-5,6-dihydro-1H,4H-pyrrolo[3,2,1-ij]quinolin-2-one::MLS000589708::SMR000219468::cid_5293996

SMILES CC1(C)CC(C)(c2ccccc2)c2cccc3\C(C(=O)N1c23)=C1\SC(=S)NC1=O

InChI Key InChIKey=GGUKORRAAAWTGU-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50195   

LigandPNGBDBM50195(4,4,6-Trimethyl-1-[4-oxo-2-thioxo-thiazolidin-(5Z)...)
Affinity DataIC50: 1.18E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50195(4,4,6-Trimethyl-1-[4-oxo-2-thioxo-thiazolidin-(5Z)...)
Affinity DataIC50: 5.31E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50195(4,4,6-Trimethyl-1-[4-oxo-2-thioxo-thiazolidin-(5Z)...)
Affinity DataIC50: 5.31E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50195(4,4,6-Trimethyl-1-[4-oxo-2-thioxo-thiazolidin-(5Z)...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50195(4,4,6-Trimethyl-1-[4-oxo-2-thioxo-thiazolidin-(5Z)...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay