BDBM50195235 CHEMBL3900409::US10287258, Example 2::US10669245, Example 2::US11117874, Example 2::US11655221, Example 2::US11680049, Example 2::US20230278969, Example 2::US20240083888, Compound AZD7986

SMILES: Cn1c2cc(ccc2oc1=O)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1

InChI Key: InChIKey=AEXFXNFMSAAELR-UHFFFAOYSA-N

Data: 34 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 50195235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin K (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 1 (Dog)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin E (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Pro-cathepsin H (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 1 (Mouse)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin D (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin G (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Rat)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin B (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin Z (Human)	BDBM50195235 (CHEMBL3900409 | US10287258, Example 2 | US10669245...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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