BDBM50196328 1-(4-tert-butylbenzyl)-3-(4-hydroxy-3-iodo-5-methoxybenzyl)thiourea::CHEMBL246651

SMILES COc1cc(CNC(=S)NCc2ccc(cc2)C(C)(C)C)cc(I)c1O

InChI Key InChIKey=RKOYYGHRKMDWAJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196328   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196328(1-(4-tert-butylbenzyl)-3-(4-hydroxy-3-iodo-5-metho...)
Affinity DataKi:  176nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of calcium uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196328(1-(4-tert-butylbenzyl)-3-(4-hydroxy-3-iodo-5-metho...)
Affinity DataKi:  342nMAssay Description:Displacement of [3H]RTX from rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed