BDBM50196690 CHEMBL224535::N-(1-(4-aminobenzyl)piperidin-3-yl)-1H-indazol-5-amine::N-[1-(4-aminobenzyl)-3-piperidyl]-N-(1H-5-indazolyl)amine

SMILES Nc1ccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)cc1

InChI Key InChIKey=XTIIQDNRAJENNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196690   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196690(CHEMBL224535 | N-(1-(4-aminobenzyl)piperidin-3-yl)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196690(CHEMBL224535 | N-(1-(4-aminobenzyl)piperidin-3-yl)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed