BDBM50196736 CHEMBL231863::benzyl (S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-difluorophenyl)-3-hydroxybutan-2-ylamino)-3-(heptan-4-ylsulfonyl)-1-oxopropan-2-ylcarbamate

SMILES CCCC(CCC)S(=O)(=O)C[C@@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNCc1cccc(CC)c1

InChI Key InChIKey=UVZYTLSBNQCQLB-BMPTZRATSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196736   

TargetCathepsin B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196736(CHEMBL231863 | benzyl (S)-1-((2S,3R)-4-(3-ethylben...)
Affinity DataIC50:  20nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196736(CHEMBL231863 | benzyl (S)-1-((2S,3R)-4-(3-ethylben...)
Affinity DataIC50:  3nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed