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BDBM50196873 CHEMBL3924218

SMILES: Cl.COc1ccc(C(=O)CC(C)C)c(OC[C@H](O)CNC(C)C)c1

InChI Key: InChIKey=ATFMDVYPKZACHW-RCHMGCFPNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50196873   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal proto-oncogene tyrosine-protein kinase Src


(Mus musculus (Mouse))
BDBM50196873
PNG
(CHEMBL3924218)
Show SMILES Cl.COc1ccc(C(=O)CC(C)C)c(OC[C@H](O)CNC(C)C)c1
Show InChI InChI=1/C18H29NO4.ClH/c1-12(2)8-17(21)16-7-6-15(22-5)9-18(16)23-11-14(20)10-19-13(3)4;/h6-7,9,12-14,19-20H,8,10-11H2,1-5H3;1H/t14-;/s2
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MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 4.09E+4n/an/an/an/an/an/a



Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL


Assay Description
Inhibition of Src in mouse BV2 cells assessed as suppression of LPS-induced NO release preincubated for 1 hr followed by LPS addition measured after ...


J Med Chem 59: 9062-9079 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00976
BindingDB Entry DOI: 10.7270/Q2B56MP4
More data for this
Ligand-Target Pair