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BDBM50197060 CHEMBL1417584

SMILES: C1CCc2c(C1)cccc2Nc1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=YYNRZIFBTOUICE-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197060   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium channel subfamily K member 18


(Homo sapiens (Human))
BDBM50197060
PNG
(CHEMBL1417584)
Show SMILES C1CCc2c(C1)cccc2Nc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C17H17N5/c1-2-8-13-12(6-1)7-5-11-15(13)18-16-10-4-3-9-14(16)17-19-21-22-20-17/h3-5,7,9-11,18H,1-2,6,8H2,(H,19,20,21,22)
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PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 6.00E+3n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Activation of human TRESK channel relative to control


Bioorg Med Chem Lett 26: 4919-4924 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.020
BindingDB Entry DOI: 10.7270/Q2T72KDN
More data for this
Ligand-Target Pair