BDBM50197224 (R)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(2-(hydroxymethyl)pyrrolidin-1-ylsulfonyl)piperidine-4-carboxamide::CHEMBL231879

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N1CCC[C@@H]1CO)C(=O)NO

InChI Key InChIKey=LOOGWNWWNBNMRC-GOSISDBHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197224   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197224((R)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-...)
Affinity DataIC50:  354nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197224((R)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197224((R)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-...)
Affinity DataIC50:  172nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed