BDBM50197506 CHEMBL3962289

SMILES CCCC[C@@H]1NC(=O)CCCCCCC(=O)NC[C@H](NC(=O)[C@H](CCCCNC(C)=S)NC1=O)C(N)=O

InChI Key InChIKey=NUQUOTOJVMERIE-UFYCRDLUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197506   

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197506(CHEMBL3962289)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of recombinant human His6-tagged SIRT3 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197506(CHEMBL3962289)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human His6-tagged SIRT2 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 12 mins in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197506(CHEMBL3962289)
Affinity DataIC50:  450nMAssay Description:Inhibition of recombinant human GST or His6-tagged SIRT1 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed