BDBM50197591 8-(2-amino-5-methyl-thiazol-4-yl)-1,2,3,11-tetrahydro-5,11-diaza-benzo[a]trindene-4,6-dione::CHEMBL245537

SMILES Cc1sc(N)nc1-c1ccc2[nH]c3c4CCCc4c4C(=O)NC(=O)c4c3c2c1

InChI Key InChIKey=JRYIOTCEXSPQBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197591   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197591(8-(2-amino-5-methyl-thiazol-4-yl)-1,2,3,11-tetrahy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed