BDBM50197883 CHEBI:78538::FX-1006::Tafamidis::US10377729, Compound Tafamidis::US20240150297, Compound Tafamadis::Vyndaqel

SMILES: OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=TXEIIPDJKFWEEC-UHFFFAOYSA-N

Data: 1 KI  13 IC50  15 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50197883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	274	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Transthyretin (TTR) (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AT-rich interactive domain-containing protein 4A (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	278	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Albumin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Albumin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	278	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinol-binding protein 4 (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM50197883 (CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair