BDBM50198036 ((R)-1-{4-[2-(4-methoxy-phenyl)-ethyl]-benzenesulfonylamino}-2-methyl-propyl)-phosphonic acid::CHEMBL228141

SMILES COc1ccc(CCc2ccc(cc2)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O)cc1

InChI Key InChIKey=AGSXHHFUSDGSSO-LJQANCHMSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50198036   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198036(((R)-1-{4-[2-(4-methoxy-phenyl)-ethyl]-benzenesulf...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198036(((R)-1-{4-[2-(4-methoxy-phenyl)-ethyl]-benzenesulf...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198036(((R)-1-{4-[2-(4-methoxy-phenyl)-ethyl]-benzenesulf...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198036(((R)-1-{4-[2-(4-methoxy-phenyl)-ethyl]-benzenesulf...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198036(((R)-1-{4-[2-(4-methoxy-phenyl)-ethyl]-benzenesulf...)
Affinity DataIC50:  480nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198036(((R)-1-{4-[2-(4-methoxy-phenyl)-ethyl]-benzenesulf...)
Affinity DataIC50:  110nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed