BDBM50198038 CHEMBL227824::[(R)-1-(4'-ethoxy-biphenyl-4-sulfonylamino)-2-methyl-propyl]-phosphonic acid

SMILES CCOc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)P(O)(O)=O

InChI Key InChIKey=RVKPGECPCLBLDB-GOSISDBHSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50198038   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  450nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  12nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  450nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed