BDBM50198086 CHEMBL3985313

SMILES CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(NC(=O)CCCC(O)=O)c2)C(=O)N1C

InChI Key InChIKey=AMBKKVYXYHXOQB-NCNSWMIJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198086   

TargetAurora kinase A(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50198086(CHEMBL3985313)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50198086(CHEMBL3985313)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed