BDBM50198269 3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)methyl)-1H-indole::CHEMBL246438

SMILES COC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1

InChI Key InChIKey=KEFPLNQTZDBPPV-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50198269   

TargetD(4) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198269(3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)met...)
Affinity DataKi:  34.1nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198269(3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)met...)
Affinity DataKi:  68.1nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198269(3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)met...)
Affinity DataKi:  262nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198269(3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)met...)
Affinity DataEC50:  34.7nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50198269(3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)met...)
Affinity DataEC50:  248nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed