BDBM50198392 1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)urea::CHEMBL439399

SMILES CC1(C)[C@@H]2C[C@H]1C(CN1CCC(CC1)NC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)=CC2

InChI Key InChIKey=YBMDKMCHOKBOLB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198392   

TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50198392(1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(((1R,5S)-...)
Affinity DataKi:  26nMAssay Description:Antagonist activity at human CXCR3 by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50198392(1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(((1R,5S)-...)
Affinity DataKi:  73nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Mouse)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50198392(1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(((1R,5S)-...)
Affinity DataKi:  400nMAssay Description:Antagonist activity at mouse CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50198392(1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(((1R,5S)-...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed