BDBM50198941 1-butyl-3-(2-hydroxy-2-methyl-propyl)-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride::CHEMBL535172

SMILES CCCCN1C(=O)C(CC(C)(C)O)NC(=O)C11CCN(Cc2ccc(Oc3ccccc3)cc2)CC1

InChI Key InChIKey=IRXUDUAPLGUWQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198941   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198941(1-butyl-3-(2-hydroxy-2-methyl-propyl)-9-(4-phenoxy...)
Affinity DataIC50:  79nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as inhibition of MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50198941(1-butyl-3-(2-hydroxy-2-methyl-propyl)-9-(4-phenoxy...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed