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BDBM50199013 3,5-dichloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo-4H-chromen-8-yl]-2-hydroxybenzenesulfonamide::CHEMBL223453::cid_6096218

SMILES: Oc1ccc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2O)c2oc(cc(=O)c12)-c1ccccc1Cl

InChI Key: InChIKey=HMNLBODGLBXMJO-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50199013   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))
BDBM50199013
PNG
(3,5-dichloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2O)c2oc(cc(=O)c12)-c1ccccc1Cl
Show InChI InChI=1S/C21H12Cl3NO6S/c22-10-7-13(24)20(28)18(8-10)32(29,30)25-14-5-6-15(26)19-16(27)9-17(31-21(14)19)11-3-1-2-4-12(11)23/h1-9,25-26,28H
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 3.40E+3n/an/an/an/an/an/a



Emory University

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q23X8539
More data for this
Ligand-Target Pair
POsterior Segregation family member (pos-1)


(Caenorhabditis elegans)
BDBM50199013
PNG
(3,5-dichloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2O)c2oc(cc(=O)c12)-c1ccccc1Cl
Show InChI InChI=1S/C21H12Cl3NO6S/c22-10-7-13(24)20(28)18(8-10)32(29,30)25-14-5-6-15(26)19-16(27)9-17(31-21(14)19)11-3-1-2-4-12(11)23/h1-9,25-26,28H
PDB

KEGG

UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q28G8J4C
More data for this
Ligand-Target Pair
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (Human))
BDBM50199013
PNG
(3,5-dichloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2O)c2oc(cc(=O)c12)-c1ccccc1Cl
Show InChI InChI=1S/C21H12Cl3NO6S/c22-10-7-13(24)20(28)18(8-10)32(29,30)25-14-5-6-15(26)19-16(27)9-17(31-21(14)19)11-3-1-2-4-12(11)23/h1-9,25-26,28H
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.40E+4n/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin A


Bioorg Med Chem 15: 702-13 (2006)


Article DOI: 10.1016/j.bmc.2006.10.063
BindingDB Entry DOI: 10.7270/Q2XK8F6Z
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50199013
PNG
(3,5-dichloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2O)c2oc(cc(=O)c12)-c1ccccc1Cl
Show InChI InChI=1S/C21H12Cl3NO6S/c22-10-7-13(24)20(28)18(8-10)32(29,30)25-14-5-6-15(26)19-16(27)9-17(31-21(14)19)11-3-1-2-4-12(11)23/h1-9,25-26,28H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 5.16E+4n/an/an/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...


PubChem Bioassay (2008)


Article DOI: 10.1021/cb400452z
BindingDB Entry DOI: 10.7270/Q27H1H0J
More data for this
Ligand-Target Pair
RecName: Full=Zinc finger protein mex-5


(Caenorhabditis elegans)
BDBM50199013
PNG
(3,5-dichloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2O)c2oc(cc(=O)c12)-c1ccccc1Cl
Show InChI InChI=1S/C21H12Cl3NO6S/c22-10-7-13(24)20(28)18(8-10)32(29,30)25-14-5-6-15(26)19-16(27)9-17(31-21(14)19)11-3-1-2-4-12(11)23/h1-9,25-26,28H
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 4.54E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2D798VP
More data for this
Ligand-Target Pair