BDBM50199105 CHEMBL2430706

SMILES Clc1cccc(COc2ccc3CCC(=O)Nc3c2)c1

InChI Key InChIKey=YODAVEOGBVTERT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199105   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50199105(CHEMBL2430706)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50199105(CHEMBL2430706)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of recombinant human MAO-B assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline after 20 mins by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50199105(CHEMBL2430706)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed