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BDBM50199581 (1-(4-chlorophenoxy)-9-(((3R,4S)-1-cyclopropyl-3-fluoropiperidin-4-yl)methyl)-9H-carbazol-3-yl)(4-methylpiperazin-1-yl)methanone::CHEMBL395640

SMILES: CN1CCN(CC1)C(=O)c1cc(Oc2ccc(Cl)cc2)c2n(C[C@@H]3CCN(C[C@@H]3F)C3CC3)c3ccccc3c2c1

InChI Key: InChIKey=KBPLHOJDAIGXOI-ZTOMLWHTSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199581   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))
BDBM50199581
PNG
((1-(4-chlorophenoxy)-9-(((3R,4S)-1-cyclopropyl-3-f...)
Show SMILES CN1CCN(CC1)C(=O)c1cc(Oc2ccc(Cl)cc2)c2n(C[C@@H]3CCN(C[C@@H]3F)C3CC3)c3ccccc3c2c1
Show InChI InChI=1S/C33H36ClFN4O2/c1-36-14-16-37(17-15-36)33(40)23-18-28-27-4-2-3-5-30(27)39(20-22-12-13-38(21-29(22)35)25-8-9-25)32(28)31(19-23)41-26-10-6-24(34)7-11-26/h2-7,10-11,18-19,22,25,29H,8-9,12-17,20-21H2,1H3/t22-,29-/m0/s1
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Similars

Article
PubMed
n/an/a 186n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [125]peptide YY from human recombinant Y1 receptor expressed in CHO cells


Bioorg Med Chem Lett 17: 1043-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.034
BindingDB Entry DOI: 10.7270/Q20C4VDN
More data for this
Ligand-Target Pair