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BDBM50199825 3-isobutyl-2-(3-(4-vinylphenyl)pyridin-4-yl)thiazolidin-4-one::CHEMBL234915

SMILES: CC(C)CN1C(SCC1=O)c1ccncc1-c1ccc(C=C)cc1

InChI Key: InChIKey=GRPUZHCGDQUWQT-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199825   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated calcium channel subunit alpha Cav2.2


(Homo sapiens (Human))
BDBM50199825
PNG
(3-isobutyl-2-(3-(4-vinylphenyl)pyridin-4-yl)thiazo...)
Show SMILES CC(C)CN1C(SCC1=O)c1ccncc1-c1ccc(C=C)cc1
Show InChI InChI=1/C20H22N2OS/c1-4-15-5-7-16(8-6-15)18-11-21-10-9-17(18)20-22(12-14(2)3)19(23)13-24-20/h4-11,14,20H,1,12-13H2,2-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 530n/an/an/an/an/an/a



Ionix Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibition of calcium channel Cav2.2 in IMR32 cells


Bioorg Med Chem Lett 17: 662-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.098
BindingDB Entry DOI: 10.7270/Q26W99Q0
More data for this
Ligand-Target Pair