BindingDB logo
myBDB logout

BDBM50199847 2-(4-(4-bromophenyl)pyridin-3-yl)-3-cyclohexylthiazolidin-4-one::CHEMBL412849

SMILES: Brc1ccc(cc1)-c1ccncc1C1SCC(=O)N1C1CCCCC1

InChI Key: InChIKey=IMUCSPIWXNWALG-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199847   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated calcium channel subunit alpha Cav2.2


(Homo sapiens (Human))
BDBM50199847
PNG
(2-(4-(4-bromophenyl)pyridin-3-yl)-3-cyclohexylthia...)
Show SMILES Brc1ccc(cc1)-c1ccncc1C1SCC(=O)N1C1CCCCC1
Show InChI InChI=1/C20H21BrN2OS/c21-15-8-6-14(7-9-15)17-10-11-22-12-18(17)20-23(19(24)13-25-20)16-4-2-1-3-5-16/h6-12,16,20H,1-5,13H2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.32E+3n/an/an/an/an/an/a



Ionix Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibition of calcium channel Cav2.2 in IMR32 cells


Bioorg Med Chem Lett 17: 662-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.098
BindingDB Entry DOI: 10.7270/Q26W99Q0
More data for this
Ligand-Target Pair