BDBM50199883 3,4‐Dichloroisocoumarin (2)::3,4-Dichloro-isochromen-1-one::3,4-dichloro-1H-isochromen-1-one::3,4-dichloroisocoumarin::CHEMBL24983::cid_1609

SMILES: c1ccc2c(c1)C(=C(OC2=O)Cl)Cl

InChI Key: InChIKey=SUGXUUGGLDCZKB-UHFFFAOYSA-N

Data: 19 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50199883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rhomboid protease GluP [F193S,L370F,L379S,R499W] (Bacillus subtilis (strain 168))	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	7.4	37
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Chymotrypsin-like elastase family member 2A (Pig)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsin-like elastase family member 2A (Rat)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil elastase (Human)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Lysosomal protective protein (Human)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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Liver carboxylesterase (Pig)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil elastase (Human)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsinogen A (Bovine)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Rhomboid-related protein 3 (Mouse)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	7.4	37
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Rhomboid-related protein 1 (Mouse)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	7.4	37
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Mitochondrial import inner membrane translocase subunit TIM10 (Baker's yeast)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Rhomboid protease GlpG (Haemophilus influenzae (g-Proteobacteria))	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	660	n/a	n/a	n/a	n/a	7.4	37
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Rhomboid protease GlpG (Escherichia coli (strain K12))	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	7.4	37
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Rhomboid protease AarA (Providencia stuartii)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.4	37
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GlpG protein (Vibrio cholerae)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	7.4	37
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Rhomboid domain-containing protein (Thermotoga maritima (strain ATCC 43589 / MSB8 / DS...)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.4	37
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Rhomboid domain-containing protein (Pyrococcus horikoshii (strain ATCC 700860 / DSM 12...)	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.4	37
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AN1-type domain-containing protein (Archaeoglobus fulgidus (AfROM))	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	7.4	37
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Rhomboid domain-containing protein (Aquifex aeolicus (strain VF5))	BDBM50199883 (cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.4	37
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