BDBM82018 CAS_790::CHEMBL1427::Hypoxanthine::NSC_790

SMILES: O=c1[nH]cnc2nc[nH]c12

InChI Key: InChIKey=FDGQSTZJBFJUBT-UHFFFAOYSA-N

Data: 2 KI  1 Kd  2 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Bovine)	BDBM82018 (CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM82018 (CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Rat)	BDBM82018 (CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 82018

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Purine nucleoside phosphorylase (Human)	BDBM82018 (CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine)	GoogleScholar			-7.40	n/a	n/a	5.43	7.40	25
TBA					Details of this binding reaction
Purine nucleoside phosphorylase (Human)	BDBM82018 (CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine)	GoogleScholar			n/a	n/a	-30.6	n/a	7.40	27
TBA					Details of this binding reaction