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BDBM50200226 CHEMBL226355::N-(2,4-dichlorophenyl)-4-(4-(2-methoxyphenyl)piperazin-1-yl)butanamide

SMILES: COc1ccccc1N1CCN(CCCC(=O)Nc2ccc(Cl)cc2Cl)CC1

InChI Key: InChIKey=ZCTIKWDKXFRMTQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200226   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated T-type calcium channel


(Homo sapiens (Human))
BDBM50200226
PNG
(CHEMBL226355 | N-(2,4-dichlorophenyl)-4-(4-(2-meth...)
Show SMILES COc1ccccc1N1CCN(CCCC(=O)Nc2ccc(Cl)cc2Cl)CC1
Show InChI InChI=1S/C21H25Cl2N3O2/c1-28-20-6-3-2-5-19(20)26-13-11-25(12-14-26)10-4-7-21(27)24-18-9-8-16(22)15-17(18)23/h2-3,5-6,8-9,15H,4,7,10-14H2,1H3,(H,24,27)
PDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.34E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp method


Bioorg Med Chem 15: 1409-19 (2007)


Article DOI: 10.1016/j.bmc.2006.11.004
BindingDB Entry DOI: 10.7270/Q2J67GKQ
More data for this
Ligand-Target Pair