BDBM50200392 CHEMBL383899::Cyclopropanecarboxylic acid-(3-(4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino)-phenyl)-amide::N-3-4-3-trifluoromethyl)phenylamino)pyrimidin-2-ylamino)phenyl)cyclopropanecarboxamide::N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE

SMILES: c1cc(cc(c1)Nc2ccnc(n2)Nc3cccc(c3)NC(=O)C4CC4)C(F)(F)F

InChI Key: InChIKey=RDTDWGQDFJPTPD-UHFFFAOYSA-N

Data: 9 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50200392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Interferon-induced, double-stranded RNA-activated protein kinase (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	591	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50200392 (N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMID...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	887	n/a	n/a	n/a	n/a	n/a	n/a
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