BDBM50200393 CHEMBL216260::N-3-2-3-trifluoromethyl)phenylamino)pyrimidin-4-ylamino)phenyl)cyclopropanecarboxamide

SMILES FC(F)(F)c1cccc(Nc2nccc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1

InChI Key InChIKey=ZJYUMCJZQBEWOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200393   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Activesight

Curated by ChEMBL
LigandPNGBDBM50200393(CHEMBL216260 | N-3-2-3-trifluoromethyl)phenylamino...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Activesight

Curated by ChEMBL
LigandPNGBDBM50200393(CHEMBL216260 | N-3-2-3-trifluoromethyl)phenylamino...)
Affinity DataIC50:  931nMAssay Description:Inhibition of Aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed