BDBM50200600 (+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::(-)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one::CHEMBL238833

SMILES COCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O

InChI Key InChIKey=HODPFCFYQOZXPB-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50200600   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200600((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200600((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200600((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200600((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200600((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200600((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [3H]naltrindole from human DOP receptor expressed in deltaC6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200600((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...)
Affinity DataIC50:  27nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200600((+)-1-methoxymethyl-3-{1-[3-(5-methoxy-2-methylphe...)
Affinity DataIC50:  27nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed