BDBM50200841 CHEMBL220360::MK-0364::MK-0634::N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide::N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide::TARANABANT::Taranbant

SMILES: C[C@@H]([C@@H](Cc1ccc(cc1)Cl)c2cccc(c2)C#N)NC(=O)C(C)(C)Oc3ccc(cn3)C(F)(F)F

InChI Key: InChIKey=QLYKJCMUNUWAGO-UHFFFAOYSA-N

Data: 2 KI  22 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50200841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.302	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rat)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.930	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	285	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rat)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM50200841 (CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair