BDBM50201389 3-methyl-5-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethoxy)phenyl)isoxazole-4-carboxamide::CHEMBL391671

SMILES Cc1noc(NCc2ccncc2)c1C(=O)Nc1cccc(OC(F)(F)F)c1

InChI Key InChIKey=HIVRIAMFVGJSGK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201389   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201389(3-methyl-5-(pyridin-4-ylmethylamino)-N-(3-(trifluo...)
Affinity DataIC50:  5.66E+3nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201389(3-methyl-5-(pyridin-4-ylmethylamino)-N-(3-(trifluo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201389(3-methyl-5-(pyridin-4-ylmethylamino)-N-(3-(trifluo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed