BDBM50201496 CHEMBL239592::N-(3-chlorophenyl)-2-oxo-2,3-dihydrobenzo[d]oxazole-4-carboxamide

SMILES Clc1cccc(NC(=O)c2cccc3oc(=O)[nH]c23)c1

InChI Key InChIKey=MARRFCXGCZHDLK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201496   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50201496(CHEMBL239592 | N-(3-chlorophenyl)-2-oxo-2,3-dihydr...)
Affinity DataKi:  68nMAssay Description:Binding affinity to mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50201496(CHEMBL239592 | N-(3-chlorophenyl)-2-oxo-2,3-dihydr...)
Affinity DataIC50:  195nMAssay Description:Antagonist activity at mGluR5 assessed as inhibition of Ca2+ efflux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed