BDBM50201563 CHEMBL3920063

SMILES CCCc1c(C#N)c(nc2[nH]nc(-c3ccccc3)c12)-c1ccccc1

InChI Key InChIKey=OWHLZKYXXOIHCQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201563   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50201563(CHEMBL3920063)
Affinity DataEC50:  53nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed